Combined effects of acrobatic exercise and magnetic stimulation on the functional recovery after spinal cord lesions

Author(s): Ahmed Z, Wieraszko A

Abstract

The objective of the study was to determine whether physical exercise combined with epidural spinal cord magnetic stimulation could improve recovery after injury of the spinal cord. Spinal cord lesioning in mice resulted in reduced locomotor function and negatively affected the muscle strength tested in vitro. Acrobatic exercise attenuated the behavioral effects of spinal cord injury. The exposure to magnetic fields facilitated further this improvement. The progress in behavioral recovery was correlated with reduced muscle degeneration and enhanced muscle contraction. The acrobatic exercise combined with stimulation with magnetic fields significantly facilitates behavioral recovery and muscle physiology in mice following spinal cord injury.

Similar Articles

Induction of vertebrate regeneration by a transient sodium current

Author(s): Tseng AS, Beane WS, Lemire JM, Masi A, Levin M

Plasticity in the intrinsic excitability of cortical pyramidal neurons

Author(s): Desai NS, Rutherford LC, Turrigiano GG

AMPA receptor-induced local brain-derived neurotrophic factor signaling mediates motor recovery after stroke

Author(s): Clarkson AN, Overman JJ, Zhong S, Mueller R, Lynch G, et al.

The role of injury discharge in the induction of neuropathic pain behavior in rats

Author(s): Seltzer Z, Beilin BZ, Ginzburg R, Paran Y, Shimko T

ATP release from dorsal spinal cord synaptosomes: characterization and neuronal origin

Author(s): Sawynok J, Downie JW, Reid AR, Cahill CM, White TD

Spinal cord injury immediately decreases anesthetic requirements in rats

Author(s): Foffani G, Humanes-Valera D, Calderon-Muñoz F, Oliviero A, Aguilar J

The effect of glutamate receptor blockers on glutamate release following spinal cord injury

Author(s): McAdoo DJ, Hughes MG, Nie L, Shah B, Clifton C, et al.

Pulmonary vasodilation by ketamine is mediated in part by L-type calcium channels

Author(s): Kaye AD, Banister RE, Anwar M, Feng CJ, Kadowitz PJ, et al.

Neuroprotective effects of riluzole and ketamine during transient spinal cord ischemia in the rabbit

Author(s): Lips J, de Haan P, Bodewits P, Vanicky I, Dzoljic M, et al.

The involvement of the mu-opioid receptor in ketamine-induced respiratory depression and antinociception

Author(s): Sarton E, Teppema LJ, Olievier C, Nieuwenhuijs D, Matthes HW, et al.

Role of kappa-opioid receptors in the effects of salvinorin A and ketamine on attention in rats

Author(s): Nemeth CL, Paine TA, Rittiner JE, Béguin C, Carroll FI, et al.

Calcium-dependent glutamate release concomitant with massive potassium flux during cerebral ischemia in vivo

Author(s): Katayama Y, Kawamata T, Tamura T, Hovda DA, Becker DP, et al.

Regional distribution and postnatal changes of D-amino acids in rat brain

Author(s): Hamase K, Homma H, Takigawa Y, Fukushima T, Santa T, et al.

Characterization of electrically evoked [3H]-D-aspartate release from hippocampal slices

Author(s): Savage DD, Galindo R, Queen SA, Paxton LL, Allan AM

Spinal cord injury causes a wide-spread, persistent loss of Kir4

Author(s): Olsen ML, Campbell SC, McFerrin MB, Floyd CL, Sontheimer H

Long-term potentiation and contextual fear conditioning increase neuronal glutamate uptake

Author(s): Levenson J, Weeber E, Selcher JC, Kategaya LS, Sweatt JD, et al.

Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation

Author(s): Correia SS, Bassani S, Brown TC, Lisé MF, Backos DS, et al.

Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals

Author(s): Williams JM, Guévremont D, Mason-Parker SE, Luxmanan C, Tate WP, et al.

Effect of intravenous lidocaine on experimental spinal cord injury

Author(s): Kobrine AI, Evans DE, LeGrys DC, Yaffe LJ, Bradley ME

Effect of lidocaine treatment on acute spinal cord injury

Author(s): Haghighi SS, Chehrazi BB, Higgins RS, Remington WJ, Wagner FC

Protection against experimental ischemic spinal cord injury

Author(s): Robertson CS, Foltz R, Grossman RG, Goodman JC