Author(s): Wilson SJ, Creswell KG, Sayette MA, Fiez JA
Many cigarette smokers appear to experience ambivalence about smoking, defined as the simultaneous co-occurrence of a strong desire to smoke and a strong wish to quit smoking. Research suggests that this ambivalence about smoking affects how smokers respond to cigarette-related stimuli, but many important questions remain about precisely how smoking ambivalence influences cognitive and affective processing during cigarette cue exposure. We used functional magnetic resonance imaging (fMRI) to address this knowledge gap by examining the relation between self-reported ambivalence about smoking and cue-reactivity in quitting-motivated smokers presented with an opportunity to smoke. Eighty-two quitting-motivated cigarette smokers completed a measure assessing their ambivalence about smoking. Subsequently, participants initiated an attempt to quit smoking and underwent an fMRI session, during which they were asked to hold and view a cigarette. Consistent with hypotheses, results indicated that self-reported smoking ambivalence was negatively correlated with cigarette-related activation in brain areas linked to reward-related processing, motivation, and attention (i.e., rostral anterior cingulate and medial prefrontal cortex, caudate nucleus, visual cortex). Self-reported ambivalence was not, however, correlated with activation in brain regions related to conflict processing. This pattern of results is discussed with respect to the process of change for those attempting to quit smoking.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/22483100
Author(s): Palfai TP, Monti PM, Ostafin B, Hutchison K
Author(s): Harrison EL, Hinson RE, McKee SA
Author(s): Howell A, Leyro T, Hogan J, Buckner J, Zvolensky M
Author(s): Krukowski RA, Solomon LJ, Naud S
Author(s): Reed MB, Wang R, Shillington AM, Clapp JD, Lange JE
Author(s): Hughes JR, Kalman D
Author(s): Hurt RD, Offord KP, Croghan IT, Gomez-Dahl L, Kottke TE, et al.
Author(s): Lisha NE, Carmody TP2, Humfleet GL2, Delucchi KL2
Author(s): Taylor B, Rehm J
Author(s): Jarvis CM, Hayman LL, Braun LT, Schwertz DW, Ferrans CE, et al.
Author(s): Joseph AM, Willenbring ML, Nugent SM, Nelson DB
Author(s): Kodl M, Fu SS, Joseph AM
Author(s): Fu S, Kodl M, Willenbring M, Nelson D, Nugent S, et al.
Author(s): Holt LJ, Litt MD, Cooney NL
Author(s): Centers for Disease Control and Prevention (CDC)
Author(s): Irving LM, Seidner AL, Burling TA, Thomas RG, Brenner GF
Author(s): Macnee CL, Talsma A
Author(s): Orleans CT, Rimer BK, Cristinzio S, Keintz MK, Fleisher L
Author(s): Asher MK, Martin RA, Rohsenow DJ, MacKinnon S, Traficante R, et al.
Author(s): Martin RA, Rohsenow DJ, MacKinnon SV, Abrams DB, Monti PM
Author(s): Velicer WF, DiClemente CC, Prochaska JO, Brandenburg N
Author(s): DiClemente CC, Prochaska JO
Author(s): Curry SJ, Grothaus L, McBride C
Author(s): Baha M, Le Faou AL
Author(s): Curry SJ, McBride C, Grothaus LC, Louie D, Wagner EH
Author(s): Saunders JB, Aasland OG, Babor TF, de la Fuente JR, Grant M
Author(s): Brown RA, Lejuez CW, Kahler CW, Strong DR
Author(s): Heatherton TF, Kozlowski LT, Frecker RC, Fagerström KO
Author(s): Pomerleau CS, Carton SM, Lutzke ML, Flessland KA, Pomerleau OF
Author(s): Filbey FM, Claus E, Audette AR, Niculescu M, Banich MT, et al.
Author(s): Fleming MF, Barry KL, MacDonald R
Author(s): Cherpitel CJ
Author(s): Macnee CL, Talsma A
Author(s): Curry S, Wagner EH, Grothaus LC
Author(s): McBride CM, Pollak KI, Bepler G, Lyna P, Lipkus IM, et al.
Author(s): Bonn-Miller MO, Zvolensky MJ
Author(s): Buckner JD, Zvolensky MJ, Schmidt NB
Author(s): Agrawal A, Budney AJ, Lynskey MT
Author(s): Degenhardt L, Hall W, Lynskey M
Author(s): Schane RE, Glantz SA, Ling PM
Author(s): DaniJA, De Biasi M
Author(s): Nestler EJ
Author(s): Ehrman RN, Robbins SJ, Bromwell MA, Lankford ME, Monterosso JR, et al.
Author(s): Wiers RW, Rinck M, Kordts R, Houben K, Strack F
Author(s): Korte KJ, Capron DW, Zvolensky M, Schmidt NB