Author(s): Parvez T
The standard treatment for glioblastoma multiforme is surgery, radiation, and chemotherapy. Yet this aggressive therapy has only a modest effect on survival with most patients surviving less than 1 year after diagnosis. This poor prognosis has lead scientists to seek alternative molecular approaches for the treatment of glioblastoma multiforme. Among these, gene therapy, vaccine therapy, and immunotherapy are all approaches that are currently being investigated. While these molecular approaches may not herald an immediate change in the prognosis of these aggressive tumors, combining them with existing approaches may bring some progress in the standard of care. This paper reviews current treatments and several newer therapies in preclinical and early clinical studies.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/18473496
Author(s): Ostrom QT, Gittleman H, Farah P, Ondracek A, Chen Y, et al.
Author(s): Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, et al.
Author(s): Fouladi M, Hunt DL, Pollack IF, Dueckers G, Burger PC, et al.
Author(s): Nelson D, Nelson J, Davis D, Chang C, Griffins T, et al.
Author(s): Reese TS, Karnovsky MJ
Author(s): Kreuter J
Author(s): Kreuter J.
Author(s): Delpassand ES, Samarghandi A, Zamanian S, Wolin EM, Hamiditabar M, et al.
Author(s): Humm JL, Sartor O, Parker C, Bruland OS, Macklis R
Author(s): Shore ND
Author(s): Parker C, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, et al.
Author(s): Chanda N, Kan P, Watkinson LD, Shukla R, Zambre A, et al.
Author(s): Bhattacharyya S, Bhattacharya R, Curley S, McNiven MA, Mukherjee P
Author(s): Arvizo RR, Miranda OR, Thompson MA, Pabelick CM, Bhattacharya R, et al.
Author(s): Arvizo RR, Miranda OR, Moyano DF, Walden CA, Giri K, et al.
Author(s): Bhattacharyya S, Singh RD, Pagano R, Robertson JD, Bhattacharya R, et al.
Author(s): Kudgus RA, Walden CA, McGovern RM, Reid JM, Robertson JD, et al.
Author(s): Kennel SJ, Chappell LL, Dadachova K, Brechbiel MW, Lankford TK, et al.
Author(s): McLaughlin MF, Robertson D, Pevsner PH, Wall JS, Mirzadeh S, et al.
Author(s): Woodward J, Kennel SJ, Stuckey A, Osborne D, Wall J, et al.
Author(s): McLaughlin MF, Woodward J, Boll RA, Wall JS, Rondinone AJ, et al.
Author(s): Miller DC, Koslow M, Budzilovich GN, Burstein DE
Author(s): Joshi RP, Hu Q
Author(s): Joshi RP, Schoenbach KH
Author(s): Roth CC, Tolstykh GP, Payne JA, Kuipers MA, Thompson GL