Author(s): Igidbashian S, Boveri S, Spolti N, Radice D, Sandri MT, et al.
Background: Human papillomavirus (HPV) testing can be used as a primary test for cervical cancer screening. HPV self-sampling has the potential to replace physician/nurse sampling. Our objective was to compare the acceptability of two self-sampling methods among 205 women undergoing an excisional procedure for cervical intraepithelial neoplasia (CIN) at the European Institute of Oncology (IEO).
Methods: One hundred eleven patients were given a Hybrid Capture (HC) Cervical Sampler™ (Qiagen, Hilden, Germany), and 94 received a self-lavaging device, the Delphi® Screener (Delphi Bioscience, Scherpenzeel, The Netherlands), both with written instructions. Self-sampling was performed just before the clinician-collected cervical sample. Women responded to questions using 5-point ordinal scales on the general acceptability of self-sampling and the physical comfort, embarrassment, pain, and difficulty experienced. Participants were also asked whether they prefer self-sampling or clinician sampling.
Results: Both self-sampling methods were generally accepted with a significantly high score (p = 0.005) and significantly lower embarrassment (p = 0.042) in favor of the Delphi Screener. Both self-sampling methods were physically well accepted, not painful, and easy to perform. Most women (n = 117, 68%) preferred the self-sampled compared to the clinician-sampled test, with a significantly higher proportion in the Delphi Screener group (n = 59, 77.6%) compared to those using the HC Sampler (n = 58, 60.4%) (p = 0.021).
Conclusions: The present study shows that self-sampling for HPV testing is favorably received by women. A sampling device specifically developed for self-sampling, such as the Delphi Screener, shows the highest degree of satisfaction. A well-accepted HPV sampling method could be especially useful for women who do not take part in cervical screening or in settings where organized screening is not fully implemented.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/21351869
Author(s): Safaeian M, Kiddugavu M, Gravitt PE, Ssekasanvu J, Murokora D, et al.
Author(s): Lack N, West B, Jeffries D, Ekpo G, Morison L, et al.
Author(s): Jones HE, Wiegerinck MA, Nieboer TE, Mol BW, Westhoff CL
Author(s): Deleré Y, Schuster M, Vartazarowa E, Hänsel T, Hagemann I, et al.
Author(s): Petignat P, Faltin DL, Bruchim I, Tramèr MR, Franco EL, et al.
Author(s): Mollers M, Scherpenisse M, van der Klis FR, King AJ, van Rossum TG, et al.
Author(s): Chranioti A, Aga E, Margari N, Kottaridi C, Pappas A, et al.
Author(s): Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, et al.
Author(s): Solomon D, Davey D, Kurman R, Moriarty A, O'Connor D, et al.
Author(s): Petignat P, Hankins C, Walmsley S, Money D, Provencher D, et al.
Author(s): Jones HE, Allan BR, van de Wijgert JH, Altini L, Taylor SM, et al.
Author(s): Kahn JA, Slap GB, Huang B, Rosenthal SL, Wanchick AM, et al.
Author(s): Karwalajtys T, Howard M, Sellors JW, Kaczorowski J
Author(s): Agorastos T, Dinas K, Lloveras B, Font R, Kornegay JR, et al.
Author(s): Baldwin S, Santos C, Mendez Brown E, Nuño T, Giuliano A, et al.
Author(s): Snijders PJ, Verhoef VM, Arbyn M, Ogilvie G, Minozzi S, et al.
Author(s): Castle PE, Rodriguez AC, Porras C, Herrero R, Schiffman M, et al.
Author(s): De Alba I, Anton-Culver H, Hubbell FA, Ziogas A, Hess JR, et al.
Author(s): Sellors JW, Lorincz AT, Mahony JB, Mielzynska I, Lytwyn A, et al.
Author(s): Enerly E, Olofsson C, Nygård M
Author(s): Szarewski A, Cadman L, Ashdown-Barr L, Waller J
Author(s): Petignat P, Vassilakos P
Author(s): Widdice LE, Moscicki AB
Author(s): American College of Obstetricians and Gynecologists
