Leiomyosarcoma of the skin, treatment of 34 cases

Author(s): Bernstein SC, Roenigk RK


background Leiomyosarcoma is a rare soft tissue sarcoma that is one of the least common malignant lesions found in the skin.

objective We discuss the clinical, histopathologic, and prognostic factors related to superficial leiomyosarcoma from cases reported in the literature as well as from the Mayo Clinic experience from 1964 through 1994 with 34 patients.

conclusions The vast majority of tumors were treated by excisional surgery with wide margins, but conceptually, Mohs' micrographic surgery should prove useful for the treatment of this tumor as it has with other skin cancers displaying contiguous growth.

Similar Articles

Leiomyosarcoma of the uterus: A clinicopathologic multicenter study of 71 cases

Author(s): Mayerhofer K, Obermair A, Windbichler G

Malignant transformation of leiomyoma of uterus to leiomyosarcoma with metastasis to ovary

Author(s): Bharambe BM, Deshpande KA, Surase SG, Ajmera AP

Malignant transition of uterine leiomyomata

Author(s): Rotmensch J, Bosnyak S, Montag A

Leiomyosarcoma of the skin and subcutaneous tissue

Author(s): Fields JP, Helwig EB

Superficial leiomyosarcoma treated with Mohs micrographic surgery

Author(s): Humphreys TR, Finkelstein DH, Lee JB

Primary leiomyosarcoma of the skin: A comprehensive review on diagnosis and treatment

Author(s): Zacher M, Heppt MV, Brinker TJ, Hayani KM, Flaig MJ, et al.