Author(s): Brown MT, Foos B
Background: Compared to adults, children maybe more highly exposed to toxic substances in drinking water because they consume more water per unit of body weight. The U.S. Environmental Protection Agency (USEPA) has developed new guidance for selecting age groups and age-specific exposure factors for assessing children's exposures and risks to environmental contaminants. Research Aim: To demonstrate the application and importance of applying age-specific drinking water intake rates, health reference values, and exposure scenarios when assessing drinking water exposures because these approaches illustrate the potential for greater potential for adverse health effects among children. Methods: manganese, an essential nutrient and neurotoxicant, was selected as a case study and chemical of potential concern for children's health. A screening-level risk assessment was performed using age-specific drinking water intake rates and manganese concentrations from U.S. public drinking water systems. Results: When age-specific drinking water intake rates are used to calculate dose, formula-fed infants receive the highest dose of manganese from drinking water compared to all other age groups. Estimated hazard quotients suggest adverse health effects are possible. Use of USEPA's standardized childhood age groups and childhood exposure factors significantly improves the understanding of childhood exposure and risks.
Author(s): Ismail HM
Author(s): Domingo JL, Bocio A, Falcó G, Llobet JM
Author(s): Mahaffey KR
Author(s): Augustsson K, Michaud DS, Rimm EB, Leitzmann MF, Stampfer MJ, et al.
Author(s): Wolk A, Larsson SC, Johansson JE, Ekman P
Author(s): Mozaffarian D, Rimm EB
Author(s): Hosseini Alhashemi A, Karbassi A, Hassanzadeh Kiabi B, Monavari SM, et al.
Author(s): Mason RP, Laporte J, Andres S
Author(s): Uluozlu OD, Tuzen M, Mendil D, Soylak M
Author(s): Turyk ME, Bhavsar SP, Bowerman W, Boysen E, Clark M, et al.
Author(s): Burger J, Gochfeld M
Author(s): Ling MP, Hsu HT, Shie RH, Wu CC, Hong YS
Author(s): Storelli MM
Author(s): Mallin MA, McIver MR, Fulton M, Wirth E
Author(s): Fraga CG
Author(s): Biswas S, Prabhu RK, Hussain KJ, Selvanayagam M, Satpathy KK
Author(s): Thiyagarajan D, Dhaneesh KV, Ajith Kumar TT, Kumaresan S, Balasubramanian T
Author(s): Sönmez AY, Yaganoglu AM, Arslan G, Hisar O
Author(s): Javed M, Usmani N
Author(s): Turan C, Dural M, Oksuz A, Oztürk B
Author(s): Fathi HB, Othman MS, Mazlan AG, Arshad A, Amin SMN, et al.
Author(s): Copat C, Bella F, Castaing M, Fallico R, Sciacca S, et al.
Author(s): Wyrzykowska B, Falandysz J, Jarzyńska G
Author(s): Strøm M, Mortensen EL, Henriksen TB, Olsen SF
Author(s): Mansilla-Rivera I, Rodríguez-Sierra CJ
Author(s): De TK, De M, Das S, Ray R, Ghosh PB
Author(s): Rejomon G, Nair M, Joseph T
Author(s): Mohan M, Deepa M, Ramasamy EV, Thomas AP
Author(s): Singh AK, Srivastava SC, Ansari A, Kumar D, Singh R
Author(s): Morra P, Bagli S, Spadoni G
Author(s): Chatterjee S, Chetia M, Singh L, Chattopadhyay B, Datta S, et al.
Author(s): Chatterjee S, Singh L, Chattopadhyay B, Datta S, Mukhopadhyay SK
Author(s): Speedy AW
Author(s): Chatterjee S, Chattopadhyay B, Mukhopadhyay SK
Author(s): Purkait S, Ganguly M, Aktar W, Sengupta D, Chowdhury A
Author(s): Adhikari S, Ghosh L, Rai SP, Ayyappan S
Author(s): Bhattacharyya S, Chaudhuri P, Dutta S, Santra SC
Author(s): Kumar B, Senthil Kumar K, Priya M, Mukhopadhyay DP, Shah R
Author(s): Kumar B, Shah R, Mukherjee D
Author(s): Gupta N, Khan DK, Santra SC
Author(s): Mukherjee D, Mukherjee A, Kumar B
Author(s): Yusof AM, Yanta NF, Wood AKH
Author(s): Bhattacharya AK, Mandal SN, Das SK
Author(s): Aktar MW, Sengupta D, Chowdhury A
Author(s): Mukherjee DP, Kumar B
Author(s): Pal M, Ghosh S, Mukhopadhyay M, Ghosh M
Author(s): Mitra A, Chowdhury R, Banerjee K
Author(s): Sarkar SK, Saha M, Takada H, Bhattacharya A, Mishra P, et al.
Author(s): Kwokal Z, Sarkar SK, Chatterjee M, Franciskovis-Bilinski S, Bilinski H, et al.
Author(s): Chakraborty R, Zaman S, Mukhopadhyay N, Banerjee K, Mitra A
Author(s): Chatterjee M, Massolo S, Sarkar SK, Bhattacharya AK, Bhattacharya BD, et al.
Author(s): Alagarsamy R, Zhang J
Author(s): Marwaha RK, Tandon N, Ganie MA, Kanwar R, Shivaprasad C, et al.
Author(s): Cooper CB, Doyle ME, Kipp K
Author(s): Al Sayegh Petkovšek S, Mazej Grudnik Z, Pokorny B
Author(s): Kar S, Maity JP, Jean JS, Liu CC, Liu CW, et al.
Author(s): Soto-Jiménez MF, Amezcua F, González-Ledesma R
Author(s): Zhuang P, Li ZA, McBride MB, Zou B, Wang G