Author(s): Lin C, Bowen P, Hoo J
Two cases of familial paracentric inversion, one in the long arm of chromosome 2 and the other in the long arm of chromosome 8, are described. The first was ascertained in a woman who was studied because of recurrent abortions. The second was ascertained in the father of a girl with the trichorhinophalangeal syndrome and an interstitial deletion in 8q. The latter is the first case in which unequal crossing over in an inversion loop can be inferred in a male carrier of a paracentric inversion. The reasons for the relatively low frequency of paracentric inversions observed and factors which affect the pregnancy outcome are discussed.
Author(s): Fryns JP, van den Berghe H
Author(s): Madan K
Author(s): Pettenati MJ, Rao PN, Phelan MC, Grass F, Rao KW, et al.
Author(s): Vialard F, Delanete A, Clement P, Simon-Bouy B, Aubriot FX, et al.
Author(s): Saito-Ohara F, Fukuda Y, Ito M, Agarwala KL, Hayashi M, et al.
Author(s): Bhatt SS, Manvelyan M, Moradkhani K, Hunstig F, Mrasek K, et al.
Author(s): Yapan C, Beyazyurek C, Ekmekci C, Kahraman S
Author(s): Amiel A, Sardos-Albertini F, Fejgin MD, Sharony R, Diukman R, et al.
Author(s): Anton E, Vidal F, Egozcue J, Blanco J
Author(s): Brown GM, Leversha M, Hulten M, Ferguson-Smith MA, Affara NA, et al.
Author(s): Madan K, Seabright M, Lindenbaum RH, Bobrow M
Author(s): Madan K, Pieters MH, Kuyt LP, van Asperen CJ, de Pater JM, et al.
