Author(s): Hanif MW, Valsamakis G, Dixon A, Boutsiadis A, Jones AF, et al.
Aim: We tested a stepwise, community-based screening strategy for glucose intolerance in South Asians using a health questionnaire in conjunction with body mass index (BMI). Anthropometric measurements (waist and hip circumference, sagittal diameter and percentage body fat) were then conducted in a hospital setting followed by an oral glucose tolerance test (OGTT) to identify subjects at the highest risk and analyse the factors predicting that risk.
Methods: A health questionnaire was administered to 435 subjects in a community setting and BMI was measured. Subjects were graded by a risk score based on the health questionnaire as high, medium and low. Subjects with high and medium risk scores and a representative sample of those with low scores had anthropometric measurements in hospital followed by an OGTT. In total, 205 (47%) of the subjects had an OGTT performed.
Results: In total, 48.7% of the subjects tested with an OGTT had evidence of glucose dysregulation: 20% had diabetes and 28.7% had impaired glucose tolerance (IGT). Logistic regression model explained 49.1% of the total variability. The significant predictors of diabetes and IGT were Blood Glucose Monitoring Strips (BMI), random blood glucose (BM), sibling with diabetes and presence of diagnosed hypertension or ischaemic disease. Most of these predictors along with other heredity diabetes factors create a composite score, with high predictability, as the receiver operating curve analysis shows.
Conclusion: We describe a simple, stepwise strategy in a community setting, based on a health questionnaire and anthropometric measurements, to explain about 50% of cases with IGT and diabetes and diagnose about 50% of cases from the population screened. We have also identified factors that predict the risk.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/17941866
Author(s): Davis TME
Author(s): National Collaborating Centre for Chronic Conditions
Author(s): Ojo O
Author(s): Masso-Gonzalez EL, Johansson S, Wallander MA, Garcia-Rodriguez LA
Author(s): Sedgwick JEC, Pearce AJ, Gulliford MC
Author(s): Ojo O
Author(s): Alberti KG, Zimmet PZ
Author(s): Nielsen J, Christensen DL
Author(s): Gagnon AJ, McDermott S, Rigol-Chachamovich J, Bandyopadhyay M, Stray-Pedersen B, et al.
Author(s): Rosenstock J
Author(s): United Nations, General Assembly
Author(s): Leung G, Stanner S
Author(s): McKeigue PM, Shah B, Marmot MG
Author(s): NICE
Author(s): Chege MP
Author(s): Hanson MA, Gluckman PD, Ma RCW, Matzen P, Biesma RG
Author(s): Luke A, Cooper RS, Prewitt TE, Adeyemo AA, Forrester TE
Author(s): Centre for Public Health Excellence at NICE, National Collaborating Centre for Primary Care
Author(s): NICE
Author(s): Earland J, Campbell J, Srivastava A
Author(s): International Diabetes Federation (IDF-2011) IDF Diabetes Atlas
Author(s): Esposito K, Maiorino MI, Ciotola M, Di Palo C, Scognamiglio P, et al.
Author(s): Walker KZ, O’Dea K, Gomez M, Girgis S, Colagiuri R
Author(s): Nantel G
Author(s): Wyness L
Author(s): Widanagamage RD, Ekanayake S, Welihinda J
Author(s): Food and Agricultural Organisation/World Health Organisation
Author(s): Burger KNJ
Author(s): Hare-Bruun H, Nielsen BM, Grau K, Oxlund AL, Heitmann BL
Author(s): Aston LM, Gambell JM, Lee DM, Bryant SP, Jebb SA
Author(s): Hassan A, Elobeid T, Kerkadi A, Medhat M, Suheil G
Author(s): Al-Dhaheri AS, Henry CJK, Lightowler HJ, Cheik Ismail LI, Al-Hanourani HM
Author(s): Sharma S, Cruickshank JK
Author(s): Weinrich SP, Priest J, Reynolds W, Godley PA, Tuckson W, et al.
Author(s): Delisle HF, Vioque J, Gil A