Heterotopic ossification

Author(s): Shehab D1, Elgazzar AH, Collier BD

Abstract

Heterotopic Ossification is the formation of bone in atypical, extraskeletal tissues that may occur following localized trauma, following a neurological injury, or as a post-surgical complication. Patients typically present with painless loss of motion of the affected joint. 

Diagnosis is made radiographically with soft tissue ossification with sharp demarcation from surrounding soft tissues.

Treatment is focused on prevention with oral indomethacin and perioperative radiation. Surgical excision is indicated in the presence of mature lesions associated with severe loss of motion and function. 

Similar Articles

Robbins and Cotran Pathologic Basis of Disease

Author(s): Kumar V, Abbas AK, Aster JC

Acute Hematogenous Osteomyelitis in Children

Author(s): Whyte NS, Bielski RJ

Robbins Basic Pathology

Author(s): Kumar V, Abbas AK, Aster JC

Current imaging concepts in pediatric osteomyelitis

Author(s): Blickman JG, van Die CE, de Rooy JW

Current concepts in pathogenesis of acute and chronic osteomyelitis

Author(s): Beck-Broichsitter BE, Smeets R, Heiland M

Diagnosis and management of osteomyelitis

Author(s): Carek PJ, Dickerson LM, Sack JL

Osteomyelitis caused by Pantoea agglomerans in a closed fracture in a child

Author(s): Labianca L, Montanaro A, Turturro F, Calderaro C, Ferretti A

Acute osteomyelitis complicating a closed radial fracture in a child

Author(s): Veranis N, Laliotis N, Vlachos E

Vertebral osteomyelitis after a closed fracture of the spine

Author(s): Govender S, Charles RW, Ballaram RS, Achary DM

Acute osteomyelitis following closed fractures

Author(s): Canale ST, Puhl J, Watson FM, Gillespie R

Acute haematogenous infection of a closed vertebral fracture

Author(s): Marshman LA, Allison D, Molloy CJ

Anterior mediastinal abscess after closed sternal fracture

Author(s): Cuschieri J, Kralovich KA, Patton JH, Horst HM, Obeid FN, et al.

Reactivation of dormant lumbar methicillin-resistant Staphylococcus aureus osteomyelitis after 12 years

Author(s): Stevens QE, Seibly JM, Chen YH, Dickerman RD, Noel J, et al.

Neurogenic heterotopic ossification

Author(s): Jensen LL1, Halar E, Little JW, Brooke MM

Current facts of para-osteo-arthropathy (POA)

Author(s): Rossier AB, Bussat P, Infante F, Zender R, Courvoisier B, et al.

Para-osteo-arthropathies

Author(s): Chantraine A, Minaire P