Orbital and intraocular myofibroblastoma

Author(s): Costin BR, Plesec TP, Rubinstein TJ, Medina CA, Singh AD, et al.


A 66-year-old woman presented with a blind, painful, hypertensive, and proptotic left eye. Computed tomographic imaging revealed a well-circumscribed mass involving the left orbit and globe. Metastatic work-up failed to reveal extraorbital lesions and the tumor was removed in toto via an evisceration approach orbitotomy. Histopathology and immunohistochemistry were most consistent with mammary-type myofibroblastoma with fascicles of bland, uniform spindle cells that stained positive for desmin and CD34. We are not aware of previous reports of orbital or ocular myofibroblastoma. This neoplasm has not been shown to recur, undergo malignant transformation, or metastasize. Familiarity with its clinical, histopathologic, and immunohistochemical features may improve diagnostic accuracy and treatment decisions for patients presenting with similar findings.

Similar Articles

Choroidal melanoma: clinical features, classification, and top 10 pseudomelanomas

Author(s): Shields CL, Manalac J, Das C, Ferguson K, Shields JA

Secondary orbital and intraocular lymphoma treated with immunochemotherapy

Author(s): Savino G, Petroni S, Balia L, Caputo CG, Battendieri R, et al.

Simultaneous ocular and orbital involvement from metastatic bronchogenic carcinoma

Author(s): Buys R, Abramson DH, Kitchin FD, Gottlieb F, Epstein M

Co-existence of intraocular and orbital lymphoma

Author(s): Neudorfer M, Kessler A, Anteby I, Goldenberg D, Barak A

[Angiomatous choroidal and orbital lesions in a patient with Sturge Weber syndrome]

Author(s): Martínez-Gutiérrez J, López-Lancho R, Pérez-Blázquez E

Survival in extra-orbital metastatic retinoblastoma:treatment results

Author(s): Leal-Leal CA, Rivera-Luna R, Flores-Rojo M, Juárez-Echenique JC, Ordaz JC, et al.

Necrotic uveal melanoma with orbital inflammation

Author(s): Blasi MA, Giammaria D, Balestrazzi E