Author(s): Dimopoulos MA, Moulopoulos LA, Maniatis A, Alexanian R
Most patients with multiple myeloma (MM) present with symptoms, have evidence of generalized disease, and require chemotherapy promptly to reduce the malignant clone. Some patients present with a local symptom from a single plasmacytoma but no myeloma elsewhere. Such patients usually become free of symptoms after local radiotherapy. In patients with MM without symptoms, the diagnosis is made on the basis of screening laboratory tests. In patients with either solitary plasmacytoma of bone or asymptomatic MM, systemic treatment should be deferred until there is evidence of disease progression.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/10979944
Author(s): DimopoulosMA, Kiamouris C, Moulopoulos LA
Author(s): Hu K, Yahalom J
Author(s): Yuranga W, Bruno DM
Author(s): http://www
Author(s): Nofsinger YC, Mirza N, Rowan PT, Lanza D, Weinstein G
Author(s): Losa M, Terreni MR, Tresoldi M, Marcatti M, Campi A, et al.
Author(s): Jagadeesan J, Oudit D, Hardwicke J, Shariff Z, McCoubrey G, et al.
Author(s): Sinnott BP, Hatipoglu B, Sarne DH
Author(s): Elias HG, Scott J, Metheny L, Quereshy FA
Author(s): Pingali SR, Haddad RY, Saad A
Author(s): Campo E, Swedlow SH, Harris NL, Pileri S, Stein H, et al.
Author(s): Ozsahin M, Tsang RW, Poortmans P, Belkacemi Y, Bolla M,et al.
Author(s): Yang B, Yu RL, Chi XH, Lu XC
Author(s): Sonneveld P, Schmidt-Wolf IG, van der Holt B, El Jarari L, Bertsch U, et al.