Rome II: The functional gastrointestinal disorders: Diagnosis, pathophysiology and treatment: a multinational consensus

Author(s): Drossman DA, Corazziari E, Talley NJ

Abstract

While medical students can confidently hold forth on the mechanisms of the Zollinger-Ellison syndrome, a condition affecting one in a million of the population, they rarely have much to say about functional GI disorders (FGIDs), which can affect up to a quarter of the population at some stage in their life. Part of the reason is that this is a complex area, which requires the integration of pathophysiology with psychology, and even sociology. FGIDs also suffer from having no objective measurable abnormalities, so that classifications must of necessity be symptom based. The Rome process is a valiant attempt to make this area of study less confused, more consistent, and scientifically respectable. As such, it undoubtedly has had a major impact, and Rome criteria are now used for the entry into most clinical trials and studies in this area. The senior chairman claims that this process has “done for functional gastrointestinal disorders what the Diagnostic and Statistical Manual of Mental Disorders (DSM-IIII) has done for psychiatry”. While this may appear grandiose, I think it just might be true.

Similar Articles

Self-report and polysomnographic measures of sleep in women with irritable bowel syndrome

Author(s): Heitkemper M, Charman AB, Shaver J, Lentz MJ, Jarrett ME

Hyperarousal and insomnia: state of the science

Author(s): Bonnet MH, Arand DL

Increased urine catecholamines and cortisol in women with irritable bowel syndrome

Author(s): Heitkemper M, Jarrett M, Cain K, Shaver J, Bond E, et al.

Salivary alpha-amylase as a measure of endogenous adrenergic activity

Author(s): Chatterton RT Jr, Vogelsong KM, Lu YC, Ellman AB, Hudgens GA

Heart rate variability: standards of measurement, physiological interpretation and clinical use

Author(s): Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology

Testing a tripartite model: I

Author(s): Watson D, Weber K, Assenheimer JS, Clark LA, Strauss ME, et al.

The measurement of fatigue: a new instrument

Author(s): Schwartz JE, Jandorf L, Krupp LB

The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research

Author(s): Buysse DJ, Reynolds CF 3rd, Monk TH, Berman SR, Kupfer DJ

Thermoregulation in women

Author(s): Stephenson LA, Kolka MA