Author(s): Zhang J, Srivastava R, Misra R
We describe here the synthesis of a novel magnetic drug-targeting carrier characterized by a core−shell structure. The core−shell carrier combines the advantages of a magnetic core and the stimuli-responsive property of the thermosensitive biodegradable polymer shell (e.g., an on−off mechanism responsive to external temperature change). The composite nanoparticles are ∼8 nm in diameter with ∼3 nm shell. The lower critical solution temperature (LCST) is ∼38 °C as determined by UV−vis absorption spectroscopy. The carrier is composed of cross-linked dextran grafted with a poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) [dextran-g-poly(NIPAAm-co-DMAAm)] shell and superparamagnetic Fe3O4 core. Fourier transform infrared spectroscopy (FTIR) confirmed the composition of the carrier. The synthesized magnetic carrier system has potential applications in magnetic drug-targeting delivery and magnetic resonance imaging.
Referred From: https://pubs.acs.org/doi/abs/10.1021/la0636199
Author(s): Hanahan D, Weinberg RA
Author(s): Burstein HJ
Author(s): Cheon J, Lee JH
Author(s): Kayser O, Lemke A, Hernandez-Trejo N
Author(s): Cho K, Wang X, Nie S, Chen ZG, Shin DM
Author(s): Dunpall R, Lewis EA, Haigh SJ, O'Brien P, Revaprasadu N
Author(s): Cho SH, Jones BL, Krishnan S
Author(s): Dunpall R, Revaprasadu N
Author(s): Rambharose S, Kalhapure RS, Akamanchi KG, Govender T
Author(s): Zhou JD, Wang SH, Liu R, Zhou CJ, Cao K, et al.
Author(s): Sohaebuddin SK, Thevenot PT, Baker D, Eaton JW, Tang L
Author(s): Chen C, Xing G, Wang J, Zhao Y, Li B, et al.
Author(s): Brannon-Peppas L, Blanchette JO
Author(s): Ortiz R, Cabeza L, Arias JL, Melguizo C, Álvarez PJ, et al.
Author(s): Wang Y, Li P, Chen L, Gao W, Zeng F
Author(s): Mandal B, Bhattacharjee H, Mittal N, Sah H, Balabathula P,et al.
Author(s): He C, Liu D, Lin W
Author(s): Shen S, Tang H, Zhang X, Ren J, Pang Z, et al.
Author(s): Banerji B, Pramanik SK, Mandal S, Maiti NC, Chaudhuri K
Author(s): Trail PA
