Author(s): Nyquist PA, Brown RD Jr, Wiebers DO, Crowson CS, O'Fallon WM
Objective: To determine whether the time of onset of subarachnoid hemorrhage (SAH) or intracerebral hemorrhage (ICH) is associated with a time of day or season of year.
Background: Prior studies have suggested that there may be a circadian and seasonal pattern of ischemic stroke occurrence, but this is less certain for hemorrhagic stroke. Population-based data have been unavailable.
Methods: All incident ICH and SAH among residents of Rochester, MN, were ascertained. The medical records of patients were reviewed to determine the time of onset and date of occurrence. The day was divided into 8-hour periods, and the year into seasonal quartiles. Each patient was assigned a period based on the time of onset of symptoms. The data were analyzed by chi(2) analysis to determine whether there was a trend toward increased occurrence based on time period or seasonal quartile of onset.
Results: From 1960 to 1989, there were 155 cases (48 men, 107 women) of incident SAH. From 1975 to 1989, there were 137 cases (57 men, 80 women) of incident ICH. There was a significant increase in the time of onset for ICH and SAH in the 8 AM to 4 PM period (p = 0.005 and p = 0.03, respectively). The concomitant occurrence of hypertension, gender, and age did not affect the time of day of occurrence. In the analysis of seasonal variation, there was a significant increase in events during December, January, and February in the combined SAH and ICH group (p = 0.032) and a trend for SAH alone (p = 0.07) but not for ICH (p = 0.34). Hypertension and age had no impact on the association between season and the occurrence of SAH and ICH.
Conclusion: The occurrence of SAH and ICH is increased from 8 AM to 4 PM. The occurrence of hemorrhage is increased during the winter months, but this is likely limited only to SAH.
Referred From: https://www.ncbi.nlm.nih.gov/pubmed/11160954
Author(s): Best JD, Maywood ES, Smith KL, Hastings MH
Author(s): Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M
Author(s): Bargiello TA, Jackson FR, Young MW
Author(s): Shearman LP, Sriram S, Weaver DR, Maywood ES, Chaves I, et al.
Author(s): Panda S, Antoch MP, Miller BH, Su AI, Schook AB, et al.
Author(s): Muller JE, Tofler GH, Stone PH
Author(s): Tsementzis SA, Gill JS, Hitchcock ER, Gill SK, Beevers DG
Author(s): Lavery CE, Mittleman MA, Cohen MC, Muller JE, Verrier RL
Author(s): Manfredini R, Boari B, Smolensky MH, Salmi R, la Cecilia O, et al.
Author(s): Westgate EJ, Cheng Y, Reilly DF, Price TS, Walisser JA, et al.
Author(s): Anea CB, Zhang M, Stepp DW, Simkins GB, Reed G, et al.
Author(s): Rudic RD, Fulton DJ
Author(s): Marshall J
Author(s): Elliott WJ
Author(s): Pardiwalla FK, Yeolekar ME, Bakshi SK
Author(s): Turin TC, Kita Y, Rumana N, Nakamura Y, Takashima N, et al.
Author(s): Casetta I, Granieri E, Fallica E, la Cecilia O, Paolino E, et al.
Author(s): Argentino C, Toni D, Rasura M, Violi F, Sacchetti ML, et al.
Author(s): Marsh EE 3rd, Biller J, Adams HP Jr, Marler JR, Hulbert JR, et al.
Author(s): Chaturvedi S, Adams HP Jr, Woolson RF
Author(s): Marler JR, Price TR, Clark GL, Muller JE, Robertson T, et al.
Author(s): Inagawa T
Author(s): Nagakane Y, Miyashita K, Nagatsuka K, Yamawaki T, Naritomi H
Author(s): Guan JW, Chen MJ, Li H, Liu YY, You C, et al.
Author(s): Guan J, Ding Y, Liu Y, Li Y, Liu Y, et al.
Author(s): Feigin VL, Anderson CS, Rodgers A, Bennett DA
Author(s): Miranpuri AS, AktÃ¼re E, Baggott CD, Miranpuri A, UluÃ§ K, et al.
Author(s): Temes RE, Bleck T, Dugar S, Ouyang B, Mohammad Y, et al.
Author(s): Kelly-Hayes M, Wolf PA, Kase CS, Brand FN, McGuirk JM, et al.
Author(s): Inagawa T, Takechi A, Yahara K, Saito J, Moritake K, et al.
Author(s): Passero S, Reale F, Ciacci G, Zei E
Author(s): Abe T, Ohde S, Ishimatsu S, Ogata H, Hasegawa T, et al.
Author(s): Inagawa T
Author(s): Brezinski DA, Tofler GH, Muller JE, Pohjola-Sintonen S, Willich SN, et al.
Author(s): Tofler GH, Brezinski D, Schafer AI, Czeisler CA, Rutherford JD, et al.
Author(s): Panza JA, Epstein SE, Quyyumi AA
Author(s): Jain S, Namboodri KK, Kumari S, Prabhakar S
Author(s): Castilla-Guerra L, Espino-Montoro A, Fernandez-Moreno MC, Lopez-Chozas JM
Author(s): Naess H, Idicula T, Brogger J, Waje-Andreassen U, Thomassen L
Author(s): Spengos K, Vemmos K, Tsivgoulis G, Manios E, Zakopoulos N, et al.
Author(s): Li-Saw-Hee FL, Blann AD, Lip GY
Author(s): Riccio PM, Klein FR, PaganiCassarÃ¡ F, MuÃ±oz Giacomelli F, GonzÃ¡lez Toledo ME, et al.
Author(s): Takahashi JS, Hong HK, Ko CH, McDearmon EL
Author(s): Yagita K, Tamanini F, Yasuda M, Hoeijmakers JH, van der Horst GT, et al.
Author(s): Meng QJ, Logunova L, Maywood ES, Gallego M, Lebiecki J, et al.
Author(s): Preitner N, Damiola F, Lopez-Molina L, Zakany J, Duboule D, et al.